Genome stability: Keeping the centrosome cycle on track

被引：48

作者：

Winey, M

机构：

[1] Dept. Molec., Cell. Devmtl. Biol., University of Colorado at Boulder, Campus Box 347, Boulder

来源：

CURRENT BIOLOGY | 1996年 / 6卷 / 08期

关键词：

D O I：

10.1016/S0960-9822(02)00639-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The protein kinase Mps1 and p53 both function in centrosome duplication and the spindle cell-cycle checkpoint. Defects in these functions can be potent sources of genomic instability by allowing mitosis to proceed with aberrant mitotic spindles.

引用

页码：962 / 964

页数：3

共 12 条

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