Osmotic stress responses of Streptococcus mutans UA159

被引：21

作者：

Abranches, J ^{[1
]}

Lemos, JA ^{[1
]}

Burne, RA ^{[1
]}

机构：

[1] Univ Florida, Dept Oral Biol, Coll Dent, Gainesville, FL 32610 USA

来源：

FEMS MICROBIOLOGY LETTERS | 2006年 / 255卷 / 02期

关键词：

osmotic stress response; gene regulation; transport; caries; biofilm; Streptococcus mutans;

D O I：

10.1111/j.1574-6968.2005.00076.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The hyperosmotic stress response of Streptococcus mutans was investigated. Real-time reverse transcriptase-PCR and slot-blot analysis revealed that opuAA, opcA, Smu.2115, sodA and nox were induced after exposure to 0.4 M NaCl. Our data suggest that there is a cross-talk between osmotic and oxidative stress responses in S. mutans. Inactivation of Smu.2115, encoding a putative oxidoreductase, resulted in an acid-resistant and hydrogen peroxide-sensitive phenotype.

引用

页码：240 / 246

页数：7

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