Passive entry of a DNA molecule into a small pore

I consider a vesicle with an open pore of small radius r(p), exposed to a DNA solution. The crucial moment is the entry, when a chain end faces the pore and enters it. I discuss qualitatively the following three characteristic times: (i) the duration of the entry of one chain end (defining the minimum lifetime of the pore) tau(e) similar to 10(-4) sec, (ii) the transfection time tau(t) (the time required to be sure that one chain has gone in) tau(t) similar to hours, and (iii) the sliding time tau(S) (the time between entry of one end and entry of the other end) similar to sec. ii fortunate feature is that sliding may proceed el en if the pore tends to close itself after entry.