A novel stereoselective route to a fumagillin and ovalicin synthetic intermediate

被引：33

作者：

Picoul, W ^{[1
]}

Urchegui, R ^{[1
]}

Haudrechy, A ^{[1
]}

Langlois, Y ^{[1
]}

机构：

[1] Univ Paris Sud, CNRS, ICMO, Lab Synthese Substances Nat, F-91450 Orsay, France

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 26期

关键词：

rearrangement; metathesis; antitumour compounds;

D O I：

10.1016/S0040-4039(99)00912-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A strategy using a highly stereoselective Claisen-Ireland rearrangement followed by a Grubbs metathesis afforded in a good overall yield after further functionalisation a potentially synthetic precursor of fumagillin and ovalicin. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：4797 / 4800

页数：4

共 25 条

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