Roles of glia in the Drosophila nervous system

被引：61

作者：

Parker, RJ ^{[1
]}

Auld, VJ ^{[1
]}

机构：

[1] Univ British Columbia, Dept Zool, Vancouver, BC V6T 1Z4, Canada

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2006年 / 17卷 / 01期

关键词：

glia; axon guidance; axon pruning; blood-brain barrier; homeostasis;

D O I：

10.1016/j.semcdb.2005.11.012

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Glial cells have diverse functions that are necessary for the proper development and function of complex nervous systems. Various insects, primarily the fruit fly Drosophila melanogaster and the moth Manduca sexta, have provided useful models of glial function during development. The present review will outline evidence of glial contributions to embryonic, visual, olfactory and wing development. We will also outline evidence for non-developmental functions of insect glia including blood-brain-barrier formation, homeostatic functions and potential contributions to synaptic function. Where relevant, we will also point out similarities between the functions of insect glia and their vertebrate counterparts. (C) 2005 Elsevier Ltd. All rights reserved.

引用

页码：66 / 77

页数：12

共 134 条

[1] Time-lapse and cell ablation reveal the role of cell interactions in fly glia migration and proliferation [J].

Aigouy, B ;

Van de Bor, W ;

Boeglin, M ;

Giangrande, A .

DEVELOPMENT, 2004, 131 (20) :5127-5138

[2] Olfactory ensheathing cells of the lamina propria in vivo and in vitro [J].

Au, E ;

Roskams, AJ .

GLIA, 2003, 41 (03) :224-236

[3] GLIOTACTIN, A NOVEL TRANSMEMBRANE PROTEIN ON PERIPHERAL GLIA, IS REQUIRED TO FORM THE BLOOD-NERVE BARRIER IN DROSOPHILA [J].

AULD, VJ ;

FETTER, RD ;

BROADIE, K ;

GOODMAN, CS .

CELL, 1995, 81 (05) :757-767

[4]

AULD VJ, 1996, GLIAL CELL DEV, P229

[5] Engulfing action of glial cells is required for programmed axon pruning during Drosophila metamorphosis [J].

Awasaki, T ;

Ito, K .

CURRENT BIOLOGY, 2004, 14 (08) :668-677

[6] Stereotyped pruning of long hippocampal axon branches triggered by retraction inducers of the semaphorin family [J].

Bagri, A ;

Cheng, HJ ;

Yaron, A ;

Pleasure, SJ ;

Tessier-Lavigne, M .

CELL, 2003, 113 (03) :285-299

[7] An evaluation of synapse independence [J].

Barbour, B .

JOURNAL OF NEUROSCIENCE, 2001, 21 (20) :7969-7984

[8] A Drosophila neurexin is required for septate junction and blood-nerve barrier formation and function [J].

Baumgartner, S ;

Littleton, JT ;

Broadie, K ;

Bhat, MA ;

Harbecke, R ;

Lengyel, JA ;

ChiquetEhrismann, R ;

Prokop, A ;

Bellen, HJ .

CELL, 1996, 87 (06) :1059-1068

[9] Regulation of cell number by MAPK-dependent control of apoptosis: A mechanism for trophic survival signaling [J].

Bergmann, A ;

Tugentman, M ;

Shilo, BZ ;

Steller, H .

DEVELOPMENTAL CELL, 2002, 2 (02) :159-170

[10] Identification and structural characterization of two genes encoding glutamate transporter homologues differently expressed in the nervous system of Drosophila melanogaster [J].

Besson, MT ;

Soustelle, L ;

Birman, S .

FEBS LETTERS, 1999, 443 (02) :97-104

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