Neonatal jaundice

被引:15
作者
McKiernan, Pat [1 ]
机构
[1] Birmingham Childrens Hosp, Liver Unit, Birmingham, W Midlands, England
关键词
CHOLESTASIS; MUTATIONS;
D O I
10.1016/j.clinre.2012.03.018
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
Neonatal jaundice lasting greater than 2 weeks should be investigated. Pale stools and dark or yellow urine are evidence of liver disease, which should be urgently investigated. The neonatal hepatitis syndrome has many causes, and a structured approach to investigation is mandatory. It should be possible to confirm or exclude biliary atresia within one week, so that definitive surgery is not delayed unnecessarily. Babies with the neonatal hepatitis syndrome should have vigorous fat-soluble vitamin supplementation, including parenteral vitamin K if coagulation is abnormal. The prognosis for infants with idiopathic neonatal hepatitis and multifactorial cholestasis is excellent. (C) 2012 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:253 / 256
页数:4
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