New cytotoxic butanolides from Litsea acutivena

被引：40

作者：

Cheng, HI

Lin, WY

Duh, CY

Lee, KH

Tsai, IL

Chen, IS ^{[1
]}

机构：

[1] Kaohsiung Med Ctr, Grad Inst Nat Prod, Kaohsiung, Taiwan

[2] Natl Sun Yat Sen Univ, Inst Marine Resources, Kaohsiung 80424, Taiwan

[3] Univ N Carolina, Sch Pharm, Natl Prod Lab, Div Med Chem & Nat Prod, Chapel Hill, NC 27599 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 12期

关键词：

D O I：

10.1021/np0102298

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Six new compounds, including one nor-neolignan, dehydroxymethylailanthoidol (1), and five butanolides, litseakolide D (2), litseakolide E (3), litseakolide F (4), litseakolide G (5), and isolincomolide D (6), were isolated from the leaves of Litsea acutivena. Their structures were elucidated from spectral analyses, The butanolides (2-6) showed significant cytotoxic activity against P-388, A549, and HT-29 cell lines in vitro.

引用

页码：1502 / 1505

页数：4

共 15 条

[1]

CHANG CE, 1996, FLORA TAIWAN, V2, P433

[2]

Chen IS, 1998, PHYTOCHEMISTRY, V49, P745, DOI 10.1016/S0031-9422(98)00129-0

[3] CHEMICAL CHARACTERIZATION OF THE ORGANIC-MATTER IN FOREST SOILS BY CURIE-POINT PYROLYSIS GC MS AND PYROLYSIS FIELD-IONIZATION MASS-SPECTROMETRY [J].