Foods as risk factors for colorectal cancer:: a case-control study in Burgundy (France)

被引:72
作者
Boutron-Ruault, MC
Senesse, P
Faivre, J
Chatelain, N
Belghiti, C
Méance, S
机构
[1] Conservatoire Natl Arts & Metiers, Inst Sci & Tech Nutr & Alimentat, F-75003 Paris, France
[2] Fac Med Dijon, Registre Bourguignon Canc Digest, Dijon, France
关键词
case-control studies; colorectal cancer; diet; epidemiology;
D O I
10.1097/00008469-199906000-00011
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Although the high meat-low vegetable diet is considered the reference high-risk diet for colorectal cancer, particularly in USA communities, other at-risk dietary patterns, such as high intakes of processed meat and refined carbohydrates are emerging. Little is known about risk factors for colorectal cancer in France, a country at high risk of rectal cancer and moderately high risk of colon cancer. We compared diet of colorectal cancer cases (n = 171) and general population controls (n = 309) in Burgundy (France). Categories of intake were established by sex and based on the distributions of food intakes in controls. Odds ratios for the fourth vs first quartile of intake (OR4) were 2.0 (1.1-3.6) for refined cereal products (rice, pasta and pastry), 2.4 (1.3-4.5) for delicatessen, 2.3 (1.2-4.2) for pates,1.7 (1.1-2.8) for offal and 2.1 (1.1-4.0) for butter, lard and cream. There was no association with consumption of fresh meat (OR4 = 1.2), fish (OR4 = 1.5), egg (OR4 = 1.1) or dairy products (OR4 = 1.0). A protective effect of vegetables was only observed for left colon cancer (OR3 = 0.3; 0.1-0.6). In men, the most significant risk factors were refined cereal products, seasoning animal fats, chocolate and coffee, whereas risk factors were delicatessen, fat meat, pasta, rice, and chocolate in women. The strong association with refined cereal products is consistent with the hypothesis of a role of hyperinsulinism in colorectal carcinogenesis. The association with processed but not fresh meat suggests the importance of exogenous carcinogenesis in that area. (C) 1999 Lippincott Williams & Wilkins.
引用
收藏
页码:229 / 235
页数:7
相关论文
共 27 条
[1]   A POPULATION-BASED CASE-CONTROL STUDY OF COLORECTAL-CANCER IN MAJORCA .1. DIETARY FACTORS [J].
BENITO, E ;
OBRADOR, A ;
STIGGELBOUT, A ;
BOSCH, FX ;
MULET, M ;
MUNOZ, N ;
KALDOR, J .
INTERNATIONAL JOURNAL OF CANCER, 1990, 45 (01) :69-76
[2]   FOOD-CONSUMPTION AND CANCER OF THE COLON AND RECTUM IN NORTH-EASTERN ITALY [J].
BIDOLI, E ;
FRANCESCHI, S ;
TALAMINI, R ;
BARRA, S ;
LAVECCHIA, C .
INTERNATIONAL JOURNAL OF CANCER, 1992, 50 (02) :223-229
[3]   SUGAR, MEAT, AND FAT INTAKE, AND NONDIETARY RISK-FACTORS FOR COLON-CANCER INCIDENCE IN IOWA WOMEN (UNITED-STATES) [J].
BOSTICK, RM ;
POTTER, JD ;
KUSHI, LH ;
SELLERS, TA ;
STEINMETZ, KA ;
MCKENZIE, DR ;
GAPSTUR, SM ;
FOLSOM, AR .
CANCER CAUSES & CONTROL, 1994, 5 (01) :38-52
[4]   A COMPARISON OF 2 DIET HISTORY QUESTIONNAIRES THAT MEASURE USUAL FOOD-INTAKE [J].
BOUTRON, MC ;
FAIVRE, J ;
MILAN, C ;
LORCERIE, B ;
ESTEVE, J .
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 1989, 12 (01) :83-91
[5]  
BOUTRON MC, 1995, AM J EPIDEMIOL, V141, P1038
[6]  
DeCosse J J, 1993, Eur J Cancer Prev, V2, P105, DOI 10.1097/00008469-199303000-00003
[7]  
Dixon WJ, 1988, BMDP STAT SOFTWARE
[8]   EPIDEMIOLOGICAL EVIDENCE FOR DISTINGUISHING SUBSITES OF COLORECTAL-CANCER [J].
FAIVRE, J ;
BEDENNE, L ;
BOUTRON, MC ;
MILAN, C ;
COLLONGES, R ;
ARVEUX, P .
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 1989, 43 (04) :356-361
[9]  
Franceschi S, 1997, INT J CANCER, V72, P56, DOI 10.1002/(SICI)1097-0215(19970703)72:1&lt
[10]  
56::AID-IJC8&gt