Dynamic Susceptibility Contrast MR Imaging in Glioma: Review of Current Clinical Practice

被引:39
作者
Boxerman, Jerrold L. [1 ]
Shiroishi, Mark S. [2 ]
Ellingson, Benjamin M. [3 ]
Pope, Whitney B. [4 ]
机构
[1] Brown Univ, Rhode Isl Hosp, Alpert Med Sch, Dept Diagnost Imaging, 593 Eddy St, Providence, RI 02903 USA
[2] Univ Southern Calif, Keck Sch Med, Dept Radiol, 1520 San Pablo St,Lower Level Imaging L1600, Los Angeles, CA 90033 USA
[3] UCLA, David Geffen Sch Med, Ctr Comp Vis & Imaging Biomarkers, Dept Radiol Sci,Brain Tumor Imaging Lab, 924 Westwood Blvd,Suite 615, Los Angeles, CA 90024 USA
[4] UCLA, David Geffen Sch Med, Dept Radiol Sci, 757 Westwood Plaza,1621 East, Los Angeles, CA 90095 USA
关键词
Dynamic susceptibility contrast MR imaging (DSC-MR imaging); Cerebral blood volume (CBV); High-grade glioma; Glioblastoma; Response assessment; Pseudoprogression; Pseudoresponse; Prognosis; CEREBRAL BLOOD-VOLUME; HIGH-GRADE GLIOMAS; NEWLY-DIAGNOSED GLIOBLASTOMA; PERFUSION MRI; RECURRENT GLIOBLASTOMA; ENHANCED MR; SURVIVAL PREDICTION; BRAIN-TUMORS; AGENT EXTRAVASATION; RESPONSE ASSESSMENT;
D O I
10.1016/j.mric.2016.06.005
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
100231 [临床病理学]; 100902 [航空航天医学];
摘要
Dynamic susceptibility contrast (DSC) MR imaging, a perfusion-weighted MR imaging technique typically used in neuro-oncologic applications for estimating the relative cerebral blood volume within brain tumors, has demonstrated much potential for determining prognosis, predicting therapeutic response, and assessing early treatment response of gliomas. This review highlights recent developments using DSCMR imaging and emphasizes the need for technical standardization and validation in prospective studies in order for this technique to become incorporated into standard-of-care imaging for patients with brain tumors.
引用
收藏
页码:649 / +
页数:23
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