Origins and functions of the chlamydial inclusion

被引：163

作者：

Hackstadt, T ^{[1
]}

Fischer, ER ^{[1
]}

Scidmore, MA ^{[1
]}

Rockey, DD ^{[1
]}

Heinzen, RA ^{[1
]}

机构：

[1] NIAID,MICROSCOPY BRANCH,NIH,ROCKY MT LABS,HAMILTON,MT 59840

来源：

TRENDS IN MICROBIOLOGY | 1997年 / 5卷 / 07期

关键词：

D O I：

10.1016/S0966-842X(97)01061-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chlamydiae dissociate themselves from the endocytic pathway shortly after internalization by actively modifying the vacuole to become fusogenic with sphingomyelin-containing exocytic vesicles. Interaction with this secretory pathway appears to provide a pathogenic mechanism that allows chlamydiae to establish themselves in a site that is not destined to fuse with lysosomes.

引用

页码：288 / 293

页数：6

共 46 条

[1] CAMPBELL S, 1989, J GEN MICROBIOL, V135, P2379
[2] Characterization of the Mycobacterium tuberculosis phagosome
Clemens, DL
[J]. TRENDS IN MICROBIOLOGY, 1996, 4 (03) : 113 - 118
[3] A NUTRIENT-PERMEABLE CHANNEL ON THE INTRAERYTHROCYTIC MALARIA PARASITE
DESAI, SA
KROGSTAD, DJ
MCCLESKEY, EW
[J]. NATURE, 1993, 362 (6421) : 643 - 646
[4] EISSENBERG LG, 1981, INFECT IMMUN, V32, P889, DOI 10.1128/IAI.32.2.889-896.1981
[5] THE INTERACTION OF BACTERIA WITH MAMMALIAN-CELLS
FALKOW, S
ISBERG, RR
PORTNOY, DA
[J]. ANNUAL REVIEW OF CELL BIOLOGY, 1992, 8 : 333 - 363
[6] INTERACTION OF L CELLS AND CHLAMYDIA-PSITTACI - ENTRY OF PARASITE AND HOST RESPONSES TO ITS DEVELOPMENT
FRIIS, RR
[J]. JOURNAL OF BACTERIOLOGY, 1972, 110 (02) : 706 - +
[7] THE VARIED LIFE-STYLES OF INTRACELLULAR PATHOGENS WITHIN EUKARYOTIC VACUOLAR COMPARTMENTS
GARCIADELPORTILLO, F
FINLAY, BB
[J]. TRENDS IN MICROBIOLOGY, 1995, 3 (10) : 373 - 380
[8] GENNIS RB, 1989, BIOMEMEBRANES MOL ST
[9] LIPID-METABOLISM IN CHLAMYDIA TRACHOMATIS-INFECTED CELLS - DIRECTED TRAFFICKING OF GOLGI-DERIVED SPHINGOLIPIDS TO THE CHLAMYDIAL INCLUSION
HACKSTADT, T
SCIDMORE, MA
ROCKEY, DD
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (11) : 4877 - 4881
[10] Chlamydia trachomatis interrupts an exocytic pathway to acquire endogenously synthesized sphingomyelin in transit from the Golgi apparatus to the plasma membrane
Hackstadt, T
Rockey, DD
Heinzen, RA
Scidmore, MA
[J]. EMBO JOURNAL, 1996, 15 (05) : 964 - 977

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