Viroids:: The noncoding genomes

被引:90
作者
Flores, R [1 ]
Di Serio, F [1 ]
Hernández, C [1 ]
机构
[1] Univ Politecn Valencia, CSIC, Inst Biol Mol & Celular Plantas, Valencia 46022, Spain
来源
SEMINARS IN VIROLOGY | 1997年 / 8卷 / 01期
关键词
hammerhead ribozymes; self-cleaving RNAs; rolling-circle replication; viroids; viroid-like satellite RNAs;
D O I
10.1006/smvy.1997.0107
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Viroids are independently replicating small circular RNAs which apparently do not code for proteins. They code, in a broad sense, for a conformation which is recognized and replicated by the host cell; two viroids also express ribozyme activities which probably mediate self-cleavage of the oligomeric replicative intermediates generated by a rolling circle mechanism. Viroids are classified into subgroups according to their sequence and to the presence and type of some conserved motifs. Viroid infections which induce symptoms, do so as a result of the direct interaction of the viroid itself, or a product of its replication, with a cellular target(s) of unknown nature. (C) 1997 Academic Press.
引用
收藏
页码:65 / 73
页数:9
相关论文
共 61 条
[61]   AN INFECTIOUS VIROID RNA REPLICON EVOLVED FROM AN IN VITRO-GENERATED NONINFECTIOUS VIROID DELETION MUTANT VIA A COMPLEMENTARY DELETION IN-VIVO [J].
WASSENEGGER, M ;
HEIMES, S ;
SANGER, HL .
EMBO JOURNAL, 1994, 13 (24) :6172-6177