Immunoliposomes for the targeted delivery of antitumor drugs

被引：133

作者：

Mastrobattista, E

Koning, GA

Storm, G

机构：

[1] Univ Utrecht, Fac Pharm, UIPS, Dept Pharmaceut, NL-3508 TB Utrecht, Netherlands

[2] Univ Groningen, Fac Med Sci, Inst Drug Explorat, Dept Physiol Chem, NL-9713 AV Groningen, Netherlands

来源：

ADVANCED DRUG DELIVERY REVIEWS | 1999年 / 40卷 / 1-2期

关键词：

anticancer agents; immunoliposomes;

D O I：

10.1016/S0169-409X(99)00043-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This review presents an overview of the field of immunoliposome-mediated targeting of anticancer agents. First, problems that are encountered when immunoliposomes are used for systemic anticancer drug delivery and potential solutions are discussed. Second, an update is given of the in vivo results obtained with immunoliposomes in tumor models. Finally, new developments on the utilization of immunoliposomes for the treatment of cancer are highlighted. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：103 / 127

页数：25

共 162 条

[1]

AHMAD I, 1993, CANCER RES, V53, P1484

[2] Liposome targeting in animal models: Problems and opportunities [J].