Bisucaberin biosynthesis: an adenylating domain of the BibC multi-enzyme catalyzes cyclodimerization of N-hydroxy-N-succinylcadaverine

被引：49

作者：

Kadi, Nadia ^{[1
]}

Song, Lijiang ^{[1
]}

Challis, Gregory L. ^{[1
]}

机构：

[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

来源：

CHEMICAL COMMUNICATIONS | 2008年 / 41期

基金：

英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1039/b813029a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The bisucaberin biosynthetic gene cluster has been identified in Vibrio salmonicida and a domain from within the BibC multienzyme encoded by the cluster has been shown to catalyse ATP-dependent dimerisation and macrocyclisation of N-hydroxy-N-succinylcadaverine to form bisucaberin.

引用

页码：5119 / 5121

页数：3

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