PCR amplification of the IS6110 insertion element of Mycobacterium tuberculosis in fecal samples from patients with intestinal tuberculosis

被引：46

作者：

Balamurugan, Raniadass

Venkataraman, Subramanian

John, K. R.

Ramakrishna, Balakrishnan S.

机构：

[1] Christian Med Coll & Hosp, Dept Gastrointestinal Sci, Vellore 632004, Tamil Nadu, India

[2] Christian Med Coll & Hosp, Dept Community Hlth, Vellore 632004, Tamil Nadu, India

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2006年 / 44卷 / 05期

关键词：

D O I：

10.1128/JCM.44.5.1884-1886.2006

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

PCR amplification of insertion element IS6110 of Mycobacterium tuberculosis in fecal samples was evaluated in the diagnosis of intestinal tuberculosis (ITB). The numbers of samples that tested positive by PCR with SalI digestion were 16/18 untreated-ITB samples, 0/8 treated-ITB samples, 12/14 smear-positive pulmonary tuberculosis samples, and 0/30 control samples. The sensitivity, specificity, positive predictive value, and negative predictive value of fecal PCR were 88.8%, 100%, 100%, and 93.7%, respectively.

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页码：1884 / 1886

页数：3

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