The role of smoking and alcohol behaviour in the management of inflammatory bowel disease

被引:30
作者
Khasawneh, Mais [1 ]
Spence, Andrew D. [2 ]
Addley, Jennifer [1 ]
Allen, Patrick B. [1 ]
机构
[1] South Eastern Hlth & Social Care Trust, Belfast, Antrim, North Ireland
[2] Queens Univ Belfast, Ctr Publ Hlth, Canc Epidemiol & Hlth Serv Res Grp, Belfast, Antrim, North Ireland
关键词
Inflammatory bowel disease; Crohn's disease; Ulcerative colitis; Smoking; Alcohol; Post-operative recurrence; CROHNS-DISEASE; ULCERATIVE-COLITIS; NATURAL-HISTORY; CLINICAL-COURSE; RISK-FACTORS; INFLIXIMAB TREATMENT; CYTOKINE RESPONSES; CIGARETTE-SMOKING; DIETARY FACTORS; SHORT-TERM;
D O I
10.1016/j.bpg.2017.10.004
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
In the era of increasing use of immunosuppressive and biologic therapy for inflammatory bowel disease, environmental influences remain important independent risk factors to modify the course of the disease, affect the need for surgery and recurrence rates post-surgical resection. The effect of smoking on inflammatory bowel disease has been established over the decades, however the exact mechanism of how smoking affects remains as area of research. Alcohol is also among the socio-environmental factors which has been recognised to cause a flare of symptoms in inflammatory bowel disease patients. Nonetheless, the exact relation to date is not fully understood, and various paradoxical results from different studies are still a point of controversy. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码:553 / 559
页数:7
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