Is there a problem matching real and model CV(ISI)?

被引：13

作者：

Brown, D ^{[1
]}

Feng, JF ^{[1
]}

机构：

[1] Babraham Inst, Lab Computat Neurosci, Cambridge CB2 4AT, England

来源：

NEUROCOMPUTING | 1999年 / 26-7卷

基金：

英国生物技术与生命科学研究理事会;

关键词：

random synaptic input; variability of interspike interval; integrate and fire neuron;

D O I：

10.1016/S0925-2312(99)00010-7

中图分类号：

TP18 [人工智能理论];

学科分类号：

081104 ; 0812 ; 0835 ; 1405 ;

摘要：

Previous studies have claimed that (a) an exact balance between numbers of randomly timed EPSPs and IPSPs and (b) high numbers of such inputs are necessary in single neuron models to obtain a coefficient of variation of interspike intervals in the physiological range (i.e. between 0.5 and 1). We show here that these are not necessary. For the perfect integrate-and-fire model, 0.5 < CV(ISI) < 1 for 0.82 < r < 0.96. For the leaky integrator with reversal potentials, CV(ISI) > 0.5 whenever the ratio between the number of inhibitory and excitatory inputs, r, exceeds 0.27 for a total Poisson EPSP input rate of 10,000 Hz. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：87 / 91

页数：5

共 12 条

[1]

FELLER W, INTRO PROBABILITY TH, P196

[2]

FENG J, UNPUB NEURAL COMPUT

[3] Impact of temporal variation and the balance between excitation and inhibition on the output of the perfect integrate-and-fire model [J].

Feng, JF ;

Brown, D .

BIOLOGICAL CYBERNETICS, 1998, 78 (05) :369-376

[4] Behaviors of spike output jitter in the integrate-and-fire model [J].

Feng, JF .

PHYSICAL REVIEW LETTERS, 1997, 79 (22) :4505-4508

[5] Spike output jitter, mean firing time and coefficient of variation [J].

Feng, JF ;

Brown, D .

JOURNAL OF PHYSICS A-MATHEMATICAL AND GENERAL, 1998, 31 (04) :1239-1252

[6] RANDOM WALK MODELS FOR SPIKE ACTIVITY OF SINGLE NEURON [J].

GERSTEIN, GL ;

MANDELBROT, B .

BIOPHYSICAL JOURNAL, 1964, 4 (1P1) :41-&

[7] Integrator or coincidence detector? The role of the cortical neuron revisited [J].

Konig, P ;

Engel, AK ;

Singer, W .

TRENDS IN NEUROSCIENCES, 1996, 19 (04) :130-137

[8] ON THE INTERSPIKE INTERVALS CALCULATED FROM DIFFUSION APPROXIMATIONS OF STEINS NEURONAL MODEL WITH REVERSAL POTENTIALS [J].

MUSILA, M ;

LANSKY, P .

JOURNAL OF THEORETICAL BIOLOGY, 1994, 171 (02) :225-232

[9]

Shadlen Michael N., 1994, Current Opinion in Neurobiology, V4, P569, DOI 10.1016/0959-4388(94)90059-0

[10]

TROYER TW, 1997, NEURAL COMPUT, V9, P733

← 1 2 →