Keloids: Prevention and Management

被引：35

作者：

Sidle, Douglas M. ^{[1
]}

Kim, Haena ^{[2
]}

机构：

[1] Northwestern Univ, Dept Otolaryngol Head & Neck Surg, Feinberg Sch Med, Div Facial Plast Surg, Chicago, IL 60611 USA

[2] Northwestern Univ, Mcgaw Med Ctr, Dept Otolaryngol Head & Neck Surg, Feinberg Sch Med, Chicago, IL 60611 USA

来源：

FACIAL PLASTIC SURGERY CLINICS OF NORTH AMERICA | 2011年 / 19卷 / 03期

关键词：

Keloid; Scar management; Hypertrophic scars; Wound healing; Keloid pathophysiology; PULSED-DYE LASER; HYPERTROPHIC SCARS; SILICONE GEL; MITOMYCIN-C; 5-FLUOROURACIL; TRIAMCINOLONE; PATHOGENESIS; EXPRESSION; ASSOCIATION; COMBINATION;

D O I：

10.1016/j.fsc.2011.06.005

中图分类号：

R61 [外科手术学];

学科分类号：

100210 [外科学];

摘要：

Keloids result from an abnormal wound-healing process in which the normal regulatory pathways during tissue regeneration and scar remodeling are disrupted. While the pathogenesis of keloids continues to be investigated, numerous treatment options exist. Although prevention of keloid formation is the best management, early recognition of keloid formation is integral in treatment and prevention of recurrence. Surgical resection with adjuvant silicone gel sheeting or triamcinolone injection is common, but can still result in recurrence. New treatments include chemotherapeutics such as 5-fluorouracil, bleomycin, and mitomycin C. Although further clinical investigation is required for newer treatments, initial results are promising.

引用

页码：505 / +

页数：12

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