BiPAP in acute respiratory failure due to myasthenic crisis may prevent intubation

被引:92
作者
Rabinstein, A [1 ]
Wijdicks, EFM [1 ]
机构
[1] Mayo Med Ctr, St Marys Hosp, Neurol Neurosurg ICU, Rochester, MN USA
关键词
D O I
10.1212/01.WNL.0000033797.79530.16
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Noninvasive mechanical ventilation using bilevel positive pressure ventilation (BiPAP) has not been studied in acute respiratory failure caused by MG. Eleven episodes in nine patients were initially managed with BiPAP, and endotracheal intubation was avoided in seven of these trials. Presence of hypercapnia (PaCO2 greater than 50 mm Hg) at onset predicted BiPAP failure and subsequent intubation. Results of this preliminary study suggest that a trial of BiPAP may prevent intubation in patients with myasthenic crisis without overt hypercapnia.
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页码:1647 / 1649
页数:3
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