Safety Profile of IBD: Lymphoma Risks

被引：12

作者：

Bewtra, Meenakshi ^{[1
]}

Lewis, James D. ^{[2
]}

机构：

[1] Univ Penn, Div Gastroenterol, Dept Med, Philadelphia, PA 19104 USA

[2] Univ Penn, Ctr Clin Epidemiol & Biostat, Philadelphia, PA 19104 USA

来源：

GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 2009年 / 38卷 / 04期

关键词：

Inflammatory bowel disease; Thiopurine analogs; Lymphoma; TNF-antagonists; Hepatosplenic T cell lymphoma; INFLAMMATORY-BOWEL-DISEASE; EPSTEIN-BARR-VIRUS; T-CELL LYMPHOMA; POPULATION-BASED COHORT; NECROSIS-FACTOR-ALPHA; NON-HODGKINS-LYMPHOMA; TERM-FOLLOW-UP; CROHNS-DISEASE; RHEUMATOID-ARTHRITIS; LONG-TERM;

D O I：

10.1016/j.gtc.2009.07.004

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

This article describes the cancer risks of commonly used inflammatory bowel disease (IBD) medications, with an emphasis on hematologic malignancy risks. The increasing use of immunosuppressant therapies in the treatment of IBD has raised this question to an even greater importance. Studies evaluating these medications are complicated due to varying disease severity and concomitant use of other immunosuppressant medication. The potential risks of all therapies must be weighed against the benefits these therapies can offer these patients.

引用

页码：669 / +

页数：22

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