The fluorapatite-anorthite system in biomedicine

被引：53

作者：

Agathopoulos, S ^{[1
]}

Tulyaganov, DU ^{[1
]}

Marques, PAAP ^{[1
]}

Ferro, MC ^{[1
]}

Fernandes, MHV ^{[1
]}

Correia, RN ^{[1
]}

机构：

[1] Univ Aveiro, Dept Ceram & Glass Engn, P-3810193 Aveiro, Portugal

来源：

BIOMATERIALS | 2003年 / 24卷 / 07期

关键词：

fluorapatite; anorthite; bioceramic; glass; glass-ceramic; biocompatibility; in vitro; in vivo;

D O I：

10.1016/S0142-9612(02)00468-4

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Glasses and glass ceramics of fluorapatite-anorthite (eutectic composition) were produced and characterized in order to evaluate their potential application in biomedicine. Bio-reactivity was determined by in vitro tests by immersion of powders in simulated plasma liquids as well as by in vivo experiments by implantation in rabbits. According to the results, the investigated materials are bio-acceptable since no toxic or other harmful evidence was detected. Glass-ceramics showed remarkable inertness, whereas glasses spontaneously dissolved in SBF and after 1 week moderate formation of apatite was observed, that however ceased within a month. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1317 / 1331

页数：15

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