Synthesis of C8-adenosine adducts of arylamines using palladium catalysis

被引：39

作者：

Schoffers, E ^{[1
]}

Olsen, PD ^{[1
]}

Means, JC ^{[1
]}

机构：

[1] Western Michigan Univ, Dept Chem, Kalamazoo, MI 49008 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 26期

关键词：

D O I：

10.1021/ol016900h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] We employed palladium-catalyzed coupling procedures for the synthesis of new C8-adenosine adducts of various arylamines-(aniline, benzidine, 4-aminobiphenyl, and 2-aminofluorene).

引用

页码：4221 / 4223

页数：3

共 34 条

[1] Synthesis of biologically active N2-amine adducts of 2′-deoxyguanosine [J].

Bonala, RR ;

Shishkina, IG ;

Johnson, F .

TETRAHEDRON LETTERS, 2000, 41 (38) :7281-7284

[2] Recognition of the nonpolar base 4-methylindole in DNA by the DNA repair adenine glycosylase MutY [J].

Chepanoske, CL ;

Langelier, CR ;

Chmiel, NH ;

David, SS .

ORGANIC LETTERS, 2000, 2 (09) :1341-1344

[3] Chemical synthesis of cross-linked purine nucleosides [J].

De Riccardis, F ;

Johnson, F .

ORGANIC LETTERS, 2000, 2 (03) :293-295

[4] A general method for the synthesis of the N2- and N6- carcinogenic amine adducts of 2′-deoxyguanosine and 2′-deoxyadenosine [J].

De Riccardis, F ;

Bonala, RR ;

Johnson, F .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (45) :10453-10460

[5]

Frost CG, 1998, J CHEM SOC PERK T 1, P2615

[6]

Garner RC, 1998, MUTAT RES-FUND MOL M, V402, P67

[7]

Hartwig JF, 1998, ANGEW CHEM INT EDIT, V37, P2046, DOI 10.1002/(SICI)1521-3773(19980817)37:15<2046::AID-ANIE2046>3.0.CO

[8]

2-L

[9] Palladium-catalyzed amination of aryl halides: Mechanism and rational catalyst design [J].

Hartwig, JF .

SYNLETT, 1997, (04) :329-+

[10] Carbon-heteroatom bond-forming reductive eliminations of amines, ethers, and sulfides [J].

Hartwig, JF .

ACCOUNTS OF CHEMICAL RESEARCH, 1998, 31 (12) :852-860

← 1 2 3 4 →