Antibiotic-resistant cell-detaching Escherichia coli strains from Nigerian children

被引：18

作者：

Okeke, IN

Steinrück, H

Kanack, KJ

Elliott, SJ

Sundström, L

Kaper, JB ^{[1
]}

Lamikanra, A

机构：

[1] Univ Maryland, Sch Med, Ctr Vaccine Dev, Baltimore, MD 21201 USA

[2] Univ Maryland, Sch Med, Dept Microbiol & Immunol, Baltimore, MD 21201 USA

[3] Obafemi Awolowo Univ, Dept Pharmaceut, Ife, Nigeria

[4] Fed Inst Hlth Protect Consumers & Vet Med, D-12277 Berlin, Germany

[5] Uppsala Univ, Dept Pharmaceut Biosci, Div Microbiol, S-75123 Uppsala, Sweden

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2002年 / 40卷 / 01期

关键词：

D O I：

10.1128/JCM.40.1.301-305.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The properties of 23 cell-detaching Escherichia coli strains that were isolated from stool specimens in Nigeria are described. Common properties of the strains included the presence of genes encoding alpha-hemolysin (100%), pyelonephritis-associated pili (100%), and cytotoxic necrotizing factor 1 (70%) as well as lactose negativity (70%) and multiple antibiotic resistance (74%). Antibiotic resistance was shown in most cases to be transferable and associated with the presence of class 1 integrons. Phenotypic properties and pulsed-field gel electrophoresis analysis demonstrated that the majority of the strains, particularly multiply resistant, lactose-negative O4:H40 strains, were closely related. Multiply-resistant cell-detaching E. coli strains may represent an important reservoir for antibiotic resistance genes.

引用

页码：301 / 305

页数：5

共 30 条

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