Secretion of extracellular proteins by enterohemorrhagic Escherichia coli via a putative type III secretion system

被引：137

作者：

Jarvis, KG ^{[1
]}

Kaper, JB ^{[1
]}

机构：

[1] UNIV MARYLAND, DEPT MED, CTR VACCINE DEV, BALTIMORE, MD 21201 USA

来源：

INFECTION AND IMMUNITY | 1996年 / 64卷 / 11期

关键词：

D O I：

10.1128/IAI.64.11.4826-4829.1996

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Enterohemorrhagic and enteropathogenic Escherichia coli (EHEC and EPEC) infections result in attaching and effacing lesions on intestinal epithelial cells. Secretion of extracellular proteins via a type III secretion apparatus is necessary for the formation of attaching and effacing lesions by EPEC. We now show that EHEC also secretes polypeptides via a putative type III secretion system. The secreted EHEC proteins are recognized by rabbit antiserum raised against the proteins secreted from EPEC and by human serum from a patient infected with an EHEC O157:H7 strain.

引用

页码：4826 / 4829

页数：4

共 30 条

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