Stem cells for enhancing recovery after stroke: a review

被引：21

作者：

England, Tim

Martin, Paul ^{[2
]}

Bath, Philip M. W. ^{[1
]}

机构：

[1] Univ Nottingham, Div Stroke Med, Stroke Trials Unit, Inst Neurosci, Nottingham NG5 1PB, England

[2] Univ Nottingham, Inst Sci & Soc, Sch Social Sci, Nottingham NG5 1PB, England

来源：

INTERNATIONAL JOURNAL OF STROKE | 2009年 / 4卷 / 02期

关键词：

granulocyte-colony stimulating factor; ischaemic stroke; stem cells; COLONY-STIMULATING FACTOR; FOCAL CEREBRAL-ISCHEMIA; CORD BLOOD-CELLS; MARROW STROMAL CELLS; ENDOTHELIAL PROGENITOR CELLS; CENTRAL-NERVOUS-SYSTEM; FUNCTIONAL RECOVERY; G-CSF; PERIPHERAL-BLOOD; CD34(+) CELLS;

D O I：

10.1111/j.1747-4949.2009.00253.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

The potential application for stem cell therapy is vast, and development for use in ischaemic stroke is still in its infancy. Access to stem cells for research is contentious; however, stem cells are obtainable from both animal and human. Despite a limited understanding of their mechanisms of action, clinical trials assessing stem cells in human stroke have been performed. Trials are also underway evaluating haematopoietic precursors mobilised with granulocyte-colony stimulating factor, an approach offering an autologous means of administrating stem cells for therapeutic purposes. This review summarises current knowledge in regard to stem cells and their potential for helping improve recovery after stroke.

引用

页码：101 / 110

页数：10

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