Inhibiting inflammation in rheumatoid arthritis

被引:29
作者
Firestein, GS [1 ]
机构
[1] Univ Calif San Diego, Sch Med, Div Rheumatol Allergy & Immunol, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Sch Med, Clin Invest Inst, La Jolla, CA 92093 USA
关键词
D O I
10.1056/NEJMcibr054344
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:80 / 82
页数:3
相关论文
共 5 条
[1]   PI3Kγ inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus [J].
Barber, DF ;
Bartolomé, A ;
Hernandez, C ;
Flores, JM ;
Redondo, C ;
Fernandez-Arias, C ;
Camps, M ;
Ruckle, T ;
Schwarz, MK ;
Rodríguez, S ;
Martinez-A, C ;
Balomenos, D ;
Rommel, C ;
Carrera, AC .
NATURE MEDICINE, 2005, 11 (09) :933-935
[2]   Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis [J].
Camps, M ;
Rückle, T ;
Ji, H ;
Ardissone, V ;
Rintelen, F ;
Shaw, J ;
Ferrandi, C ;
Chabert, C ;
Gillieron, C ;
Françon, B ;
Martin, T ;
Gretener, D ;
Perrin, D ;
Leroy, D ;
Vitte, PA ;
Hirsch, E ;
Wymann, MP ;
Cirillo, R ;
Schwarz, MK ;
Rommel, C .
NATURE MEDICINE, 2005, 11 (09) :936-943
[3]   Chemokine signalling: pivoting around multiple phosphoinositide 3-kinases [J].
Curnock, AP ;
Logan, MK ;
Ward, SG .
IMMUNOLOGY, 2002, 105 (02) :125-136
[4]   Evolving concepts of rheumatoid arthritis [J].
Firestein, GS .
NATURE, 2003, 423 (6937) :356-361
[5]   Collagen type II-specific monoclonal antibody-induced arthritis in mice - Description of the disease and the influence of age, sex, and genes [J].
Nandakumar, KS ;
Svensson, L ;
Holmdahl, R .
AMERICAN JOURNAL OF PATHOLOGY, 2003, 163 (05) :1827-1837