E-optimal designs for the Michaelis-Menten model

被引:27
作者
Dette, H
Wong, WK
机构
[1] Ruhr Univ Bochum, Fak Math, D-44780 Bochum, Germany
[2] Univ Calif Los Angeles, Dept Biostat, Los Angeles, CA 90095 USA
关键词
E-optimal designs; Michaelis-Menten model; error structure;
D O I
10.1016/S0167-7152(99)00033-4
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
We construct locally E-optimal designs for the two parameter Michaelis-Menten model under various assumptions on the error structure. Illustrative examples are given and the performance of these designs are compared with D-optimal designs. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:405 / 408
页数:4
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