Synthesis of oxime-linked mucin mimics containing the tumor-related TN and sialyl TN antigens

被引：59

作者：

Marcaurelle, LA

Shin, YS

Goon, S

Bertozzi, CR ^{[1
]}

机构：

[1] Univ Calif Berkeley, Ctr New Direct Organ Synth, Dept Chem, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Ctr New Direct Organ Synth, Dept Mol & Cell Biol, Berkeley, CA 94720 USA

[3] Univ Calif Berkeley, Howard Hughes Med Inst, Berkeley, CA 94720 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 23期

关键词：

D O I：

10.1021/ol0166247

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The synthesis of oxime-linked mucin mimics was accomplished via the incorporation of multiple ketone residues into a peptide followed by reaction with aminooxy sugars corresponding to the tumor-related T-N and sialyl T-N (STN) antigens.

引用

页码：3691 / 3694

页数：4

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