Self-assembly of β-cyclodextrin in water.: Part 1:: Cryo-TEM and dynamic and static light scattering

被引：250

作者：

Bonini, M

Rossi, S

Karlsson, G

Almgren, M

Lo Nostro, P ^{[1
]}

Baglioni, P

机构：

[1] Univ Florence, Dept Chem, I-50019 Florence, Italy

[2] Univ Florence, CSGI, I-50019 Florence, Italy

[3] Uppsala Univ, Dept Phys Chem, S-75123 Uppsala, Sweden

来源：

LANGMUIR | 2006年 / 22卷 / 04期

关键词：

D O I：

10.1021/la052878f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this article, we report evidence of beta-cyclodextrin (beta-CD) self-aggregation in water. A critical aggregation concentration (cac) between 2 and 3 mM was determined by using dynamic (DLS) and static (SLS) light scattering to investigate the presence of beta-cyclodextrin aggregates. Transmission electron microscopy at cryogenic temperature (Cryo-TEM) was used to detect the structural features of cyclodextrin self-aggregates. The results show the occurrence of polymorphism depending on the beta-CD concentration: polydisperse nearly spherical objects with diameters of about 100 nm are present at lower concentrations, whereas micrometer planar aggregates are predominant at higher concentrations.

引用

页码：1478 / 1484

页数：7

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