Identification of Bdellovibrio bacteriovorus HD100 Bd0714 as a Nudix dGTPase

被引：11

作者：

Steyert, Susan R. ^{[1
]}

Messing, Simon A. J. ^{[2
]}

Amzel, L. Mario ^{[2
]}

Gabelli, Sandra B. ^{[2
]}

Pineiro, Silvia A. ^{[1
]}

机构：

[1] Univ Maryland, Sch Med, Dept Med & Res Technol, Baltimore, MD 21201 USA

[2] Johns Hopkins Univ, Sch Med, Dept Biophys & Biophys Chem, Baltimore, MD 21205 USA

来源：

JOURNAL OF BACTERIOLOGY | 2008年 / 190卷 / 24期

关键词：

D O I：

10.1128/JB.01009-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Bdellovibrio bacteriovorus bacteria are predatory organisms that attack other gram-negative bacteria. Here, we report that Bd0714 is a Nudix dGTPase from B. bacteriovorus HD100 with a substrate specificity similar to that of Escherichia coli MutT and complements an E. coli mutT-deficient strain. We observed different transcription levels of the gene throughout the predator life cycle.

引用

页码：8215 / 8219

页数：5

共 28 条

[1] A SOLUBLE ENZYME-ACTIVITY THAT ATTACHES FREE DIAMINOPIMELIC ACID TO BDELLOPLAST PEPTIDOGLYCAN [J].

ARAKI, Y ;

RUBY, EG .

BIOCHEMISTRY, 1988, 27 (07) :2624-2629

[2] The MutT proteins or ''nudix'' hydrolases, a family of versatile, widely distributed, ''housecleaning'' enzymes [J].

Bessman, MJ ;

Frick, DN ;

OHandley, SF .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (41) :25059-25062

[3]

BHATNAGAR SK, 1991, J BIOL CHEM, V266, P9050

[4]

BHATNAGAR SK, 1988, J BIOL CHEM, V263, P8953

[5] The bacterial enzyme RppH triggers messenger RNA degradation by 5' pyrophosphate removal [J].

Deana, Atilio ;

Celesnik, Helena ;

Belasco, Joel G. .

NATURE, 2008, 451 (7176) :355-U14

[6] Structure and function of the E-coli dihydroneopterin triphosphate pyrophosphatase:: A Nudix enzyme involved in folate biosynthesis [J].

Gabelli, Sandra B. ;

Bianchet, Mario A. ;

Xu, WenLian ;

Dunn, ChristopherA. ;

Niu, Zhi-Dian ;

Amzel, L. Mario ;

Bessman, Maurice J. .

STRUCTURE, 2007, 15 (08) :1014-1022

[7] The structure of ADP-ribose pyrophosphatase reveals the structural basis for the versatility of the Nudix family [J].

Gabelli, SB ;

Bianchet, MA ;

Bessman, MJ ;

Amzel, LM .

NATURE STRUCTURAL BIOLOGY, 2001, 8 (05) :467-472

[8] ESPript:: analysis of multiple sequence alignments in PostScript [J].

Gouet, P ;

Courcelle, E ;

Stuart, DI ;

Métoz, F .

BIOINFORMATICS, 1999, 15 (04) :305-308

[9] Mutational, kinetic, and NMR studies of the roles of conserved glutamate residues and of lysine-39 in the mechanism of the MutT pyrophosphohydrolase [J].

Harris, TK ;

Wu, G ;

Massiah, MA ;

Mildvan, AS .

BIOCHEMISTRY, 2000, 39 (07) :1655-1674

[10] RESPIRATION OF BDELLOVIBRIO-BACTERIOVORUS STRAIN 109J AND ITS ENERGY SUBSTRATES FOR INTRAPERIPLASMIC GROWTH [J].

HESPELL, RB ;

ROSSON, RA ;

THOMASHOW, MF ;

RITTENBERG, SC .

JOURNAL OF BACTERIOLOGY, 1973, 113 (03) :1280-1288

← 1 2 3 →