Highly enantioselective addition of ketones to nitroolefins catalyzed by new thiourea-amine bifunctional organocatalysts

被引：322

作者：

Tsogoeva, SB ^{[1
]}

Wei, SW ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

CHEMICAL COMMUNICATIONS | 2006年 / 13期

关键词：

D O I：

10.1039/b517937h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new and effective organocatalytic system: primary amine derived chiral thiourea catalyst 4a and AcOH-H2O additive, which converts different ketones to gamma-nitroketones in high yields (82-99%) and enantioselectivities (90-99%) has been described.

引用

页码：1451 / 1453

页数：3

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