Identification and analysis of phosphopeptides

被引：58

作者：

Chalmers, MJ

Kolch, W

Emmett, MR

Marshall, AG

Mischak, H

机构：

[1] Mosaiques Diagn & Therapeut AG, D-30625 Hannover, Germany

[2] Beatson Inst Canc Res, Glasgow G61 1BD, Lanark, Scotland

[3] Natl High Magnet Field Lab, Ion Cyclotron Resonance Program, Tallahassee, FL 32310 USA

来源：

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 2004年 / 803卷 / 01期

基金：

英国惠康基金; 美国国家科学基金会;

关键词：

reviews; phosphorylation; post-translational modification; phosphopeptides;

D O I：

10.1016/j.jchromb.2003.09.006

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Reversible phosphorylation of serine, threonine and tyrosine residues in proteins is one of the key events in signal transduction. To understand the process of signal transduction on a molecular level, it is imperative to identify phosphorylation sites in proteins. In this review, we offer an overview of the different methods/technologies currently available to identify protein phosphorylation sites. (C) 2003 Elsevier B.V. All riahts reserved.

引用

收藏

页码：111 / 120

页数：10

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