Study of arterial blood pressure by a Windkessel-type model:: influence of arterial functional properties

被引:18
作者
Diourté, B
Siché, JP
Comparat, V
Baguet, JP
Mallion, JM
机构
[1] IN2P3, CNRS, F-38026 Grenoble, France
[2] CHU Grenoble, F-38043 Grenoble, France
关键词
blood pressure; Windkessel; arterial properties; simulation;
D O I
10.1016/S0169-2607(99)00002-4
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Objective: to analyse the performance of a Windkessel blood pressure (BP) modeling of arterial compliance adjusted in a dynamic fashion according to a non-linear relationship between en the arterial compliance (AC) and BP. Non invasive measurements of the radial BP waveform (MILLAR tonometry) were compared to those constructed by an electric simulator reproducing the model in a symmetrical network subdivided into 121 segments. We introduced at cardiac level the aortic stroke volume (Doppler echocardiography) and the dynamic values of compliance (relation of compliance-to pressure, constant or variable) whether the model was linear or non linear, measured by high resolution Doppler (NIUS 02) for each subject. Results: at the radial artery segment the modelled BP obtained by the non linear model of AC was not significantly different from the measured BP wave, while in the linear model (AC constant at mean BP level) the systolic BP was significantly underestimated. (*P < 0.05) Conclusion: this work shows the limits inherent in simplification of arterial compliance in the Windkessel model using constant parameters. This demonstrates the influence of the dynamic properties of the arterial wall in a conduction artery on the level of systolic and diastolic BP. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:11 / 22
页数:12
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