Intolerance to Statins: Mechanisms and Management

被引:118
作者
Bitzur, Rafael [1 ]
Cohen, Hofit [1 ]
Kamari, Yehuda [1 ]
Harats, Dror [1 ]
机构
[1] Chaim Sheba Med Ctr, Bert W Strassburger Lipid Ctr, IL-52621 Tel Hashomer, Israel
关键词
SQUALENE SYNTHASE INHIBITOR; COA REDUCTASE INHIBITORS; MYOPATHY; COENZYME-Q10; CHOLESTEROL; SAFETY; TOLERABILITY; PRAVASTATIN; UBIQUINONE; SYMPTOMS;
D O I
10.2337/dcS13-2038
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
[No abstract available]
引用
收藏
页码:S325 / S330
页数:6
相关论文
共 46 条
[1]
Hydrophobic statins induce autophagy and cell death in human rhabdomyosarcoma cells by depleting geranylgeranyl diphosphate [J].
Araki, Makoto ;
Maeda, Masatomo ;
Motojima, Kiyoto .
EUROPEAN JOURNAL OF PHARMACOLOGY, 2012, 674 (2-3) :95-103
[2]
Effectiveness and tolerability of every-other-day rosuvastatin dosing in patients with prior statin intolerance [J].
Backes, James M. ;
Venero, Carmelo V. ;
Gibson, Cheryl A. ;
Ruisinger, Janelle F. ;
Howard, Patricia A. ;
Thompson, Paul D. ;
Moriarty, Patrick M. .
ANNALS OF PHARMACOTHERAPY, 2008, 42 (03) :341-346
[3]
Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials [J].
Baigent, C. ;
Blackwell, L. ;
Emberson, J. ;
Holland, L. E. ;
Reith, C. ;
Bhala, N. ;
Peto, R. ;
Barnes, E. H. ;
Keech, A. ;
Simes, J. ;
Collins, R. .
LANCET, 2010, 376 (9753) :1670-1681
[4]
Statin safety: An overview and assessment of the data-2005 [J].
Bays, H .
AMERICAN JOURNAL OF CARDIOLOGY, 2006, 97 (8A) :6C-26C
[5]
CORONARY DRUG PROJECT - EXPERIENCE WITH NIACIN [J].
BERGE, KG ;
CANNER, PL .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1991, 40 :S49-S51
[6]
Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy [J].
Boden, William E. ;
Probstfield, Jeffrey L. ;
Anderson, Todd ;
Chaitman, Bernard R. ;
Desvignes-Nickens, Patrice ;
Koprowicz, Kent ;
McBride, Ruth ;
Teo, Koon ;
Weintraub, William .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (24) :2255-2267
[7]
Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a omitohormesis' mechanism involving reactive oxygen species and PGC-1 [J].
Bouitbir, Jamal ;
Charles, Anne-Laure ;
Echaniz-Laguna, Andoni ;
Kindo, Michel ;
Daussin, Frederic ;
Auwerx, Johan ;
Piquard, Francois ;
Geny, Bernard ;
Zoll, Joffrey .
EUROPEAN HEART JOURNAL, 2012, 33 (11) :1397-1407
[8]
Mild to moderate muscular symptoms with high-dosage statin therapy in hyperlipidemic patients -: The PRIMO study [J].
Bruckert, E ;
Hayem, G ;
Dejager, S ;
Yau, C ;
Bégaud, B .
CARDIOVASCULAR DRUGS AND THERAPY, 2005, 19 (06) :403-414
[9]
Statin Use and Musculoskeletal Pain Among Adults With and Without Arthritis [J].
Buettner, Catherine ;
Rippberger, Matthew J. ;
Smith, Julie K. ;
Leveille, Suzanne G. ;
Davis, Roger B. ;
Mittleman, Murray A. .
AMERICAN JOURNAL OF MEDICINE, 2012, 125 (02) :176-182
[10]
Effect of coenzyme Q10 on myopathic symptoms in patients treated with statins [J].
Caso, Giuseppe ;
Kelly, Patricia ;
McNurlan, Margaret A. ;
Lawson, William E. .
AMERICAN JOURNAL OF CARDIOLOGY, 2007, 99 (10) :1409-1412