Quantum dots - DNA detectives

被引：37

作者：

Dubertret, B ^{[1
]}

机构：

[1] Ecole Super Phys & Chim Ind Ville Paris, CNRS, F-75231 Paris, France

来源：

NATURE MATERIALS | 2005年 / 4卷 / 11期

关键词：

D O I：

10.1038/nmat1520

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The use of quantum dots as DNA nanosensors promises to significantly enhance the sensitivity of fluorescence-based DNA detection for medical diagnosis and biomolecular investigations.

引用

页码：797 / 798

页数：2

共 8 条

[1] Thermodynamic basis of the enhanced specificity of structured DNA probes [J].

Bonnet, G ;

Tyagi, S ;

Libchaber, A ;

Kramer, FR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (11) :6171-6176

[2] Comparison of photophysical and colloidal properties of biocompatible semiconductor nanocrystals using fluorescence correlation spectroscopy [J].

Doose, S ;

Tsay, JM ;

Pinaud, F ;

Weiss, S .

ANALYTICAL CHEMISTRY, 2005, 77 (07) :2235-2242

[3] Multiple label-free biodetection and quantitative DNA-binding assays on a nanomechanical cantilever array [J].

McKendry, R ;

Zhang, JY ;

Arntz, Y ;

Strunz, T ;

Hegner, M ;

Lang, HP ;

Baller, MK ;

Certa, U ;

Meyer, E ;

Güntherodt, HJ ;

Gerber, C .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (15) :9783-9788

[4] Self-assembled nanoscale biosensors based on quantum dot FRET donors [J].

Medintz, IL ;

Clapp, AR ;

Mattoussi, H ;

Goldman, ER ;

Fisher, B ;

Mauro, JM .

NATURE MATERIALS, 2003, 2 (09) :630-638

[5]

Park SJ, 2002, SCIENCE, V295, P1503, DOI 10.1126/science.1067003

[6] The renaissance of fluorescence resonance energy transfer [J].

Selvin, PR .

NATURE STRUCTURAL BIOLOGY, 2000, 7 (09) :730-734

[7] Molecular beacons: Probes that fluoresce upon hybridization [J].

Tyagi, S ;

Kramer, FR .

NATURE BIOTECHNOLOGY, 1996, 14 (03) :303-308

[8] Single-quantum-dot-based DNA nanosensor [J].

Zhang, CY ;

Yeh, HC ;

Kuroki, MT ;

Wang, TH .

NATURE MATERIALS, 2005, 4 (11) :826-831

← 1 →