Levels of toxins in oral tobacco products in the UK

被引:47
作者
McNeill, A
Bedi, R
Islam, S
Alkhatib, MN
West, R
机构
[1] Kings Coll London, Dept Dent Publ Hlth, London, England
[2] UCL, Dept Epidemiol & Publ Hlth, London, England
关键词
D O I
10.1136/tc.2005.013011
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Objective: This study examined the constituents of smokeless tobacco products available in the UK and compared them with products available in India, Sweden, and the USA Methods: Seven UK brands of smokeless tobacco, including a tooth cleaning powder, and four international brands of smokeless tobacco were tested for a range of toxins and known carcinogens, such as tobacco specific N-nitrosamines (TSNA), as well as nicotine availability. Results: Ten of the 11 brands tested had detectable levels of tobacco specific nitrosamines, which are proven carcinogens, and levels varied 130-fold. All had detectable levels of benzo(a)pyrene, another proven carcinogen (with around 175-fold variation) and several toxic metals (with nearly 150-fold variation). Nicotine availability varied in the UK products from 0.1 mg/g to 63.2 mg/g. All the tobacco products tested are likely to be hazardous to users' health, but the data indicate that it should be possible to reduce key toxins to non-detectable levels. Conclusions: Smokeless tobacco products should be regulated and standards set for maximum levels of toxins and carcinogens.
引用
收藏
页码:64 / 67
页数:4
相关论文
共 15 条
[1]   European Union policy on smokeless tobacco:: a statement in favour of evidence based regulation for public health [J].
Bates, C ;
Fagerström, K ;
Jarvis, MJ ;
Kunze, M ;
McNeill, A ;
Ramström, L .
TOBACCO CONTROL, 2003, 12 (04) :360-367
[2]  
Bedi R, 1995, Prim Dent Care, V2, P39
[3]   ANALYTICAL STUDIES ON TOBACCO-SPECIFIC N-NITROSAMINES IN TOBACCO AND TOBACCO-SMOKE [J].
BRUNNEMANN, KD ;
HOFFMANN, D .
CRITICAL REVIEWS IN TOXICOLOGY, 1991, 21 (04) :235-240
[4]   Chemical profile of two types of oral snuff tobacco [J].
Brunnemann, KD ;
Qi, J ;
Hoffmann, D .
FOOD AND CHEMICAL TOXICOLOGY, 2002, 40 (11) :1699-1703
[5]  
Brunnemann KD QJ, 2001, AGING ORAL MOIST SNU
[6]   EFFECTS OF STORAGE-CONDITIONS ON LEVELS OF TOBACCO-SPECIFIC N-NITROSAMINES AND N-NITROSAMINO ACIDS IN UNITED-STATES MOIST SNUFF [J].
DJORDJEVIC, MV ;
FAN, JR ;
BUSH, LP ;
BRUNNEMANN, KD ;
HOFFMANN, D .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1993, 41 (10) :1790-1794
[7]   Smokeless tobacco and health in India and south Asia [J].
Gupta, PC ;
Ray, CS .
RESPIROLOGY, 2003, 8 (04) :419-431
[8]   Evaluation of carcinogen exposure in people who used "reduced exposure" tobacco products [J].
Hatsukami, DK ;
Lemmonds, C ;
Zhang, Y ;
Murphy, SE ;
Le, C ;
Carmella, SG ;
Hecht, SS .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2004, 96 (11) :844-852
[9]   5 LEADING US COMMERCIAL BRANDS OF MOIST SNUFF IN 1994 - ASSESSMENT OF CARCINOGENIC N-NITROSAMINES [J].
HOFFMANN, D ;
DJORDJEVIC, MV ;
FAN, JG ;
ZANG, E ;
GLYNN, T ;
CONNOLLY, GN .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1995, 87 (24) :1862-1869
[10]   Decreased levels of tobacco-specific N-nitrosamines in moist snuff on the Swedish market [J].
Osterdahl, BG ;
Jansson, C ;
Paccou, A .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2004, 52 (16) :5085-5088