Chimeric monoclonal anti-CD20 antibody (rituximab) - an effective treatment for a patient with relapsing hairy cell leukaemia

被引:19
作者
Hagberg, H [1 ]
机构
[1] Univ Uppsala, Akad Sjukhuset, Dept Oncol, S-75185 Uppsala, Sweden
关键词
hairy cell leukaemia; anti CD-20 antibodies; rituximab;
D O I
10.1007/BF02906136
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A case story is presented, describing a 46 y old man, with a relapsing hairy cell leukaemia. After treatment with monoclonal anti CD-20 antibodies (rituximab) 375 mg/week, four times, a complete remission was obtained which has lasted >9 months. The rituximab treatment produced a better remission than earlier treatments with alpha-interferon and chlorodeoxyadenosine. In addition, in contrast to other treatments, no initial worsening of the pancytopenia was observed.
引用
收藏
页码:221 / 222
页数:2
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