Effective cancer therapy with a single injection of interleukin-2 at the site of the tumour

被引：21

作者：

Den Otter, W

Cadée, J

Gavhumende, R

De Groot, CJ

Hennink, WE

Stewart, R

机构：

[1] Univ Utrecht, Dept Pharmaceut, NL-3508 TC Utrecht, Netherlands

[2] SPCA, Bulawayo, Zimbabwe

[3] Univ Zimbabwe, Fac Vet Sci, Harare, Zimbabwe

[4] Univ Utrecht, Dept Cell Biol & Histol, NL-3508 TD Utrecht, Netherlands

来源：

CANCER IMMUNOLOGY IMMUNOTHERAPY | 1999年 / 48卷 / 07期

关键词：

interleukin-2; IL-2; immunotherapy of cancer;

D O I：

10.1007/s002620050595

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mice with a severe metastasized tumour burden can be cured with a single local injection of interleukin-2. Such a treatment can also be effective against ocular squamous cell carcinoma in cows and transmissible venereal tumours in dogs. We did not notice any toxic effects of this treatment.

引用

页码：419 / 420

页数：2

共 12 条

[1] SINGLE-DRUG CHEMOTHERAPY OF CANINE TRANSMISSIBLE VENEREAL TUMOR WITH CYCLOPHOSPHAMIDE, METHOTREXATE, OR VINCRISTINE [J].