Aquaporin-1: a novel promoter of tumor angiogenesis

被引：43

作者：

Clapp, C ^{[1
]}

de la Escalera, GM ^{[1
]}

机构：

[1] Univ Nacl Autonoma Mexico, Inst Neurobiol, Queretaro 76230, Mexico

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 2006年 / 17卷 / 01期

关键词：

D O I：

10.1016/j.tem.2005.11.009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Angiogenesis is critical to solid tumor growth; therefore, understanding how blood vessels form within a developing tumor has become a principal, yet challenging, objective. The recent discovery that deletion of the water channel protein, aquaporin-1, impairs tumor angiogenesis provides novel insights into the mechanisms governing the neovascularization and growth of tumors.

引用

页码：1 / 2

页数：2

共 10 条

[1] Transepidermal water loss in developing rats:: Role of aquaporins in the immature skin
Ågren, J
Zelenin, S
Håkansson, M
Eklöf, AC
Aperia, A
Nejsum, LN
Nielsen, S
Sedin, G
[J]. PEDIATRIC RESEARCH, 2003, 53 (04) : 558 - 565
[2] Cellular abnormalities of blood vessels as targets in cancer
Baluk, P
Hashizume, H
McDonald, DM
[J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 2005, 15 (01) : 102 - 111
[3] Mobasheri A, 2005, INT J ONCOL, V26, P1149
[4] Global gene expression analysis to identify molecular markers of uterine receptivity and embryo implantation
Reese, J
Das, SK
Paria, BC
Lim, H
Song, H
Matsumoto, H
Knudtson, KL
DuBois, RN
Dey, SK
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (47) : 44137 - 44145
[5] Aquaporin water channel genes are differentially expressed and regulated by ovarian steroids during the periimplantation period in the mouse
Richard, C
Gao, J
Brown, N
Reese, J
[J]. ENDOCRINOLOGY, 2003, 144 (04) : 1533 - 1541
[6] MIGRATION-ASSOCIATED VOLUME CHANGES IN NEUTROPHILS FACILITATE THE MIGRATORY PROCESS IN-VITRO
ROSENGREN, S
HENSON, PM
WORTHEN, GS
[J]. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 1994, 267 (06): : C1623 - C1632
[7] Effect of estrogen on endothelial function and angiogenesis
Rubanyi, GM
Johns, A
Kauser, K
[J]. VASCULAR PHARMACOLOGY, 2002, 38 (02) : 89 - 98
[8] Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption
Saadoun, S
Papadopoulos, MC
Hara-Chikuma, M
Verkman, AS
[J]. NATURE, 2005, 434 (7034) : 786 - 792
[9] Disrupting tumour blood vessels
Tozer, GM
Kanthou, C
Baguley, BC
[J]. NATURE REVIEWS CANCER, 2005, 5 (06) : 423 - 435
[10] Aquaporin water channels and endothelial cell function
Verkman, AS
[J]. JOURNAL OF ANATOMY, 2002, 200 (06) : 617 - 627

← 1 →