Preferential Utilization of D-Lactate by Shewanella oneidensis

被引：33

作者：

Brutinel, Evan D.

Gralnick, Jeffrey A. ^{[1
]}

机构：

[1] Univ Minnesota Twin Cities, Inst Biotechnol, St Paul, MN USA

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2012年 / 78卷 / 23期

关键词：

ESCHERICHIA-COLI; DEHYDROGENASE; PURIFICATION; METABOLISM; GROWTH; LLDR;

D O I：

10.1128/AEM.02183-12

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Shewanella oneidensis couples oxidation of lactate to respiration of many substrates. Here we report that llpR (L-lactate-positive regulator, SO_3460) encodes a positive regulator of L-lactate utilization distinct from previously studied regulators. We also demonstrate D-lactate inhibition of L-lactate utilization in S. oneidensis, resulting in preferential utilization of the D isomer.

引用

页码：8474 / 8476

页数：3

共 18 条

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[2]

[Anonymous], 2012, Molecular Cloning: A Laboratory Manual

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