ABCA1 Gene Mutations, HDL Cholesterol Levels, and Risk of Ischemic Heart Disease

被引：14

作者：

Brunham, Liam R. ^{[1
,2
]}

Kastelein, John J. P. ^{[3
]}

Hayden, Michael R. ^{[1
,2
]}

机构：

[1] Univ British Columbia, Ctr Mol Med & Therapeut, Dept Med Genet, Vancouver, BC V5Z 1M9, Canada

[2] Univ British Columbia, Ctr Mol Med & Therapeut, Dept Med, Vancouver, BC V5Z 1M9, Canada

[3] Univ Amsterdam, Acad Med Ctr, Dept Vasc Med, NL-1105 AZ Amsterdam, Netherlands

来源：

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2008年 / 300卷 / 17期

关键词：

D O I：

10.1001/jama.2008.539

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

引用

页码：1997 / 1998

页数：2

共 5 条

[1]

Variations on a gene:: Rare and common variants in ABCA1 and their impact on HDL cholesterol levels and atherosclerosis [J].

Brunham, Liam R. ;

Singaraja, Roshni R. ;

Hayden, Michael R. .

ANNUAL REVIEW OF NUTRITION, 2006, 26 :105-129

[2]

Mutation in ABCA1 predicted risk of ischemic heart disease in the Copenhagen City Heart Study population [J].

Frikke-Schmidt, R ;

Nordestgaard, BG ;

Schnohr, P ;

Steffensen, R ;

Tybjærg-Hansen, A .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 46 (08) :1516-1520

[3]

Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease [J].

Frikke-Schmidt, Ruth ;

Nordestgaard, Borge G. ;

Stene, Maria C. A. ;

Sethi, Amar A. ;

Remaley, Alan T. ;

Schnohr, Peter ;

Grande, Peer ;

Tybjaerg-Hansen, Anne .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2008, 299 (21) :2524-2532

[4]

Genetic variation in ABCA1 predicts ischemic heart disease in the general population [J].

Frikke-Schmidt, Ruth ;

Nordestgaard, Borge G. ;

Jensen, Gorm B. ;

Steffensen, Rolf ;

Tybjaerg-Hansen, Anne .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2008, 28 (01) :180-186

[5]

Specific mutations in ABCA1 have discrete effects on ABCA1 function and lipid phenotypes both in vivo and in vitro [J].

Singaraja, Roshni R. ;

Visscher, Henk ;

James, Erick R. ;

Chroni, Angeliki ;

Coutinho, Jonathan M. ;

Brunham, Liam R. ;

Kang, Martin H. ;

Zannis, Vassilis I. ;

Chimini, Giovanna ;

Hayden, Michael R. .

CIRCULATION RESEARCH, 2006, 99 (04) :389-397

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