Generation of simian-tropic HIV-1 by restriction factor evasion

被引：122

作者：

Hatziioannou, Theodora

Princiotta, Michael

Piatak, Michael, Jr.

Yuan, Fang

Zhang, Fengwen

Lifson, Jeffrey D.

Bieniasz, Paul D.

机构：

[1] Aaron Diamond AIDS Res Ctr, New York, NY 10016 USA

[2] Rockefeller Univ, New York, NY 10016 USA

[3] NCI, AIDS Vaccine Program, SAIC Frederick Inc, Frederick, MD 21702 USA

来源：

SCIENCE | 2006年 / 314卷 / 5796期

关键词：

D O I：

10.1126/science.1130994

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A modified HIV-1 resistant to curtain enzymes can replicate in macaque T cells, potentially allowing the use of nonhuman primates to study AIDS.

引用

页码：95 / 95

页数：1

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