Application of HRMAS 1H NMR spectroscopy to investigate interactions between ligands and synthetic receptors

被引：36

作者：

Händel, H

Gesele, E

Gottschall, K

Albert, K

机构：

[1] Univ Tubingen, Inst Organ Chem, D-72076 Tubingen, Germany

[2] Gesell Tech Chromatog mbH, Dr Gottschall INSTRUCT, D-67059 Ludwigshafen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 04期

关键词：

D O I：

10.1002/anie.200390133

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Towards an understanding of chromatographic separation processes: The effect of the solvent composition on the strength of interaction between a chromatographic support and different organic substrates can be monitored by the relative intensity of the intramolecular negative transferred NOE effect (trNOE). The strength of interaction of different synthetic stationary phases with model substrates could be evaluated as changes in the observed trNOE (see picture Y=CH2 or NH, R1=CH3, R2=phenyl).

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页码：438 / +

页数：6

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