Epidemiology of osteoporosis in rheumatic diseases

被引:103
作者
Sinigaglia, Luigi
Varenna, Massimo
Girasole, Giuseppe
Bianchi, Gerolamo
机构
[1] Univ Milan, Gaetano Pini Inst, Dept Rheumatol, I-20122 Milan, Italy
[2] La Colletta Hosp, Bone Metab Unit, Dept Rheumatol, I-16011 Arenzano, Genova, Italy
关键词
D O I
10.1016/j.rdc.2006.07.002
中图分类号
R5 [内科学];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
Osteoporosis and related fragility fractures represent one of the most common complications that occurs in patients who have rheumatic diseases, and contributes to a dramatic decrease in quality of life. Bone is affected negatively by the disease process and often by the therapy itself in different rheumatic conditions, notably rheumatoid arthritis (RA), and the relationship between osteoporosis and osteoarthritis is a matter of concern. The clinical relevance of osteoporosis in rheumatic diseases is underestimated. Recent data demonstrated that patients who had RA and took oral corticosteroids did not undergo bone densitometry routinely. This article focuses on the burden of osteoporosis and fragility fractures in different rheumatic conditions, and emphasizes the importance of this complication for which effective preventive measures are available.
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收藏
页码:631 / +
页数:30
相关论文
共 151 条
[1]
ARE DISEASE DURATION AND DEGREE OF FUNCTIONAL IMPAIRMENT DETERMINANTS OF BONE LOSS IN RHEUMATOID-ARTHRITIS [J].
ALS, OS ;
GOTFREDSEN, A ;
RIIS, BJ ;
CHRISTIANSEN, C .
ANNALS OF THE RHEUMATIC DISEASES, 1985, 44 (06) :406-411
[2]
Antoniades L, 2000, ARTHRITIS RHEUM, V43, P1450, DOI 10.1002/1529-0131(200007)43:7<1450::AID-ANR6>3.0.CO
[3]
2-6
[4]
Arden NK, 1999, ARTHRITIS RHEUM, V42, P1378, DOI 10.1002/1529-0131(199907)42:7<1378::AID-ANR11>3.0.CO
[5]
2-I
[6]
Arden NK, 1996, BRIT J RHEUMATOL, V35, P1299
[7]
Osteopenia in men with mild and severe ankylosing spondylitis [J].
Baek, HJ ;
Kang, SW ;
Lee, YJ ;
Shin, KC ;
Lee, EB ;
Yoo, CD ;
Song, YW .
RHEUMATOLOGY INTERNATIONAL, 2005, 26 (01) :30-34
[8]
BARWELL R, 1865, DIS JOINTS
[9]
BELMONTESERRANO MA, 1993, J RHEUMATOL, V20, P1005
[10]
Osteoarthritis of the knee is associated with vertebral and nonvertebral fractures in the elderly: The Rotterdam study [J].
Bergink, AP ;
Van der Klift, M ;
Hofman, A ;
Verhaar, JAN ;
Van Leeuwen, JPTM ;
Uitterlinden, AG ;
Pols, HAP .
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH, 2003, 49 (05) :648-657