Total synthesis of angucyclines.: Part 15:: A short synthesis of (±)-6-deoxybrasiliquinone B

被引：28

作者：

Krohn, K ^{[1
]}

Micheel, J ^{[1
]}

Zukowski, M ^{[1
]}

机构：

[1] Univ Paderborn, Facbereich Chem & Chem Tech, D-33098 Paderborn, Germany

来源：

TETRAHEDRON | 2000年 / 56卷 / 27期

关键词：

Diels-Alder reaction; boron triacetate; angucycline antibiotics; brasiliquinones; dimethyldioxirane oxidation;

D O I：

10.1016/S0040-4020(00)00398-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 6-deoxybrasiliquinones 2 and 14a were prepared by a boron triacetate mediated Diels-Alder reaction of juglone (9) with the crude mixture of ethoxy dienes 6 and 7. The primary non-aromatic Diels-Alder product 10 was isolated after reaction of the dienol 8 with 9. Dimethyldioxirane oxidation of 10 afforded the epoxide 11. (C) 2000 Published by Elsevier Science Ltd.

引用

页码：4753 / 4758

页数：6

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