Synthesis of fluorescence-labeled peptidocalix[4]arene library and its peptide sensing ability

被引:18
作者
Hioki, H [1 ]
Kubo, M [1 ]
Yoshida, H [1 ]
Bando, M [1 ]
Ohnishi, Y [1 ]
Kodama, M [1 ]
机构
[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan
关键词
calixarenes; combinatorial library; chemosensors; fluorescence change;
D O I
10.1016/S0040-4039(02)01861-0
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The fluorescence spectrum of the peptidocalix[4]arene 5, which was found in the screening of library 1 against the target peptide 2a, was dependent on the concentration of 2b. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:7949 / 7952
页数:4
相关论文
共 21 条
[1]  
Bissel R.A., 1992, CHEM SOC REV, P187
[2]   PEPTIDOSTEROIDAL RECEPTORS FOR OPIOID-PEPTIDES - SEQUENCE-SELECTIVE BINDING USING A SYNTHETIC RECEPTOR LIBRARY [J].
BOYCE, R ;
LI, G ;
NESTLER, HP ;
SUENAGA, T ;
STILL, WC .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (17) :7955-7956
[3]  
Chan W., 1999, Fmoc solid phase peptide synthesis: a practical approach
[4]   Fluorescent, sequence-selective peptide detection by synthetic small molecules [J].
Chen, CT ;
Wagner, H ;
Still, WC .
SCIENCE, 1998, 279 (5352) :851-853
[5]   Sequence-selective peptide binding with a peptido-A,B-trans-steroidal receptor selected from an encoded combinatorial receptor library [J].
Cheng, YA ;
Suenaga, T ;
Still, WC .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (07) :1813-1814
[6]  
Connors K. A., 1987, BINDING CONSTANTS ME, P141
[7]  
CZARNIK AW, 1992, FLUORESCENT CHEMOSEN
[8]   Simple and rapid visual sensing of saccharides [J].
Davis, CJ ;
Lewis, PT ;
McCarroll, ME ;
Read, MW ;
Cueto, R ;
Strongin, RM .
ORGANIC LETTERS, 1999, 1 (02) :331-334
[9]   Signaling recognition events with fluorescent sensors and switches [J].
de Silva, AP ;
Gunaratne, HQN ;
Gunnlaugsson, T ;
Huxley, AJM ;
McCoy, CP ;
Rademacher, JT ;
Rice, TE .
CHEMICAL REVIEWS, 1997, 97 (05) :1515-1566
[10]   Calixarenes: Designer ligands for chemical sensors. [J].
Diamond, D ;
Nolan, K .
ANALYTICAL CHEMISTRY, 2001, 73 (01) :22A-29A