The predictive value of incidental PET/CT findings suspicious for breast cancer in women with non-breast malignancies

被引：19

作者：

Beatty, John S. ^{[1
]}

Williams, Hadyn T. ^{[2
]}

Gucwa, Angela L. ^{[1
]}

Hughes, Matthew P. ^{[3
]}

Vasudeva, Viren S. ^{[3
]}

Aldridge, Beau A. ^{[3
]}

Fields, Deborah M. ^{[2
]}

David, George S. ^{[2
]}

Lind, D. Scott ^{[1
]}

Kruse, E. James ^{[1
]}

McLoughlin, James M. ^{[1
]}

机构：

[1] Med Coll Georgia, Dept Surg, Augusta, GA 30912 USA

[2] Med Coll Georgia, Dept Radiol, Augusta, GA 30912 USA

[3] Med Coll Georgia, Sch Med, Augusta, GA 30912 USA

来源：

AMERICAN JOURNAL OF SURGERY | 2009年 / 198卷 / 04期

关键词：

PET/CT; Breast cancer; Second primary malignancy; CLINICAL-SIGNIFICANCE; COMPUTED-TOMOGRAPHY; CHILDHOOD-CANCER; FDG-PET/CT; FOLLOW-UP; RECOMMENDATIONS; RECURRENCE; GUIDELINES; MANAGEMENT; SURVIVORS;

D O I：

10.1016/j.amjsurg.2009.06.009

中图分类号：

R61 [外科手术学];

学科分类号：

100210 [外科学];

摘要：

BACKGROUND: On occasion, patients followed with positron emission tomographic (PET)/computed tomographic (CT) imaging for nonbreast malignancies will have incidental breast findings concerning for second primary breast cancers. The aim of this study was to determine the predictive value of PET/CT imaging to identify breast cancers in these patients. METHODS: Patients with primary nonbreast malignancies and findings concerning for second primary breast cancers were identified from a prospectively acquired nuclear medicine database from January 2005 to July 2008. Chart reviews were then performed. RESULTS: Nine hundred two women underwent PET/CT imaging to evaluate nonbreast malignancies. Nine women (1%) had concerning breast findings, and 5 (56%) had subsequent breast cancer diagnoses. The positive predictive value of PET/CT imaging in these patients was 63%. Evidence of compliance with current screening guidelines was present in only 22% of these patients. CONCLUSIONS: The data suggest that findings concerning for an additional primary breast cancer should be evaluated and that age-appropriate screening tools should not be abandoned. (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：495 / 499

页数：5

共 27 条

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