Nanometer-sized channel gating by a self-assembled polypeptide brush

被引：87

作者：

Ito, Y ^{[1
]}

Park, YS

Imanishi, Y

机构：

[1] Univ Tokushima, Fac Engn, Dept Biol Sci & Technol, Tokushima 7708506, Japan

[2] JST, PRESTO, Kyoto 6190237, Japan

[3] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Kyoto 6068501, Japan

[4] NAIST, Grad Sch Mat Sci, Ikoma 6300101, Japan

来源：

LANGMUIR | 2000年 / 16卷 / 12期

关键词：

D O I：

10.1021/la991102+

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A nanometer-sized signal-responsive gate was fabricated by self-assembly of ionizable polypeptide brushes on a gold-coated porous membrane, and its responsiveness in water was visualized by atomic force microscopy. The gating was regulated by the conformational change of poly(glutamic acid) that undergoes a helix-coil transition in response to pH. As a result, water permeation through the membrane was reversibly regulated by pH. The permeability could be adjusted by varying the length of the polypeptide brush. This type of membrane will be useful for the precise control of substance permeation.

引用

页码：5376 / 5381

页数：6

共 37 条

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