Data Management and Other Logistical Challenges for the GEMS: The Data Coordinating Center Perspective

被引:15
作者
Biswas, Kousick [1 ]
Carty, Christina [1 ]
Horney, Rebecca [1 ]
Nasrin, Dilruba [2 ]
Farag, Tamer H. [2 ]
Kotloff, Karen L. [2 ]
Levine, Myron M. [2 ]
机构
[1] Dept Vet Affairs, Cooperat Studies Program Coordinating Ctr, Perry Point, MD 21902 USA
[2] Univ Maryland, Sch Med, Ctr Vaccine Dev, Baltimore, MD 21201 USA
基金
比尔及梅琳达.盖茨基金会;
关键词
D O I
10.1093/cid/cis755
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
071005 [微生物学]; 100108 [医学免疫学];
摘要
The Cooperative Studies Program Coordinating Center provided the data management, administrative, and statistical support to the Global Enteric Multicenter Study (GEMS). The GEMS study, the largest epidemiological study in the diarrheal disease area among children < 5 years of age, was carried out in 4 African countries and 3 Asian countries. Given the geographical and geopolitical differences among the countries, the administration of a centralized data management operation was a major challenge. The sheer volume of the data that were collected, regular transfer of the data to a centralized database, and the cleaning of the same also posed some challenges. This paper outlines the details of the support that the data coordinating center provided and the challenges faced during the course of the study.
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页码:S254 / S261
页数:8
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