Daphnicyclidins J and K, unique polycyclic alkaloids from Daphniphyllum humile

被引：38

作者：

Morita, H ^{[1
]}

Yoshida, N ^{[1
]}

Kobayashi, J ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 07期

关键词：

D O I：

10.1021/jo0163288

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two Daphniphyllum alkaloids with unprecedented polycyclic skeletons, daphnicyclidins J (1) and K (2), have been isolated from the stems of Daphniphyllum humile, and the structures and relative stereochemistry were elucidated on the basis of spectroscopic data. The absolute stereochemistry of 1 was established by chemical correlation with a known-related alkaloid, daphynicyclidin D (3), through a modified Polonovski reaction.

引用

页码：2278 / 2282

页数：5

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