Geographic distribution of Venezuelan equine encephalitis virus subtype IE genotypes in Central America and Mexico

被引：34

作者：

Oberste, MS

Schmura, SM

Weaver, SC

Smith, JF

机构：

[1] USA, Med Res Inst Infect Dis, Frederick, MD USA

[2] Univ Texas, Med Branch, Dept Pathol, Galveston, TX 77550 USA

[3] Univ Texas, Med Branch, Ctr Trop Dis, Galveston, TX 77550 USA

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 1999年 / 60卷 / 04期

关键词：

D O I：

10.4269/ajtmh.1999.60.630

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Phylogenetic analysis of 20 strains of Venezuelan equine encephalitis (VEE) virus subtype IE isolated from 1961 to 1996 in Mexico and throughout Central America showed that VEE virus subtype IE was monophyletic with respect to other VEE virus subtypes. Nonetheless, there were at least three distinct geographically separated VEE virus LE genotypes: northwestern Panama, Pacific coast (Mexico/Guatemala), and Gulf/Caribbean coast (Mexico/Belize). Strains from the Caribbean coast of Guatemala, Honduras, and Nicaragua may cluster with the Gulf/Caribbean genotype, but additional isolates from the region between Guatemala and Panama will be required to firmly establish their phylogenetic position. Viruses associated with two separate equine epizootics in Mexico in the 1990s were phylogenetically related to nonepizootic viruses from neighboring Guatemala and may represent the emergence or re-emergence of equine-virulent VEE virus subtype IE in Middle America.

引用

页码：630 / 634

页数：5

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